BIO304 review | Yuxuan Wu

Instructions to candidates for final exam of BIO304

Don’t write your name or ID number in this document or in the file name to enable blind marking.

The examination consists of seven questions of which only FIVE questions need to be answered.

Each of the five questions answered will be awarded to a maximum of 20 marks leading to a maximum of 100 marks for this exam.

Type your answer directly below the appropriate question in this document and follow the instructions regarding maximum word limits.

You are allowed to use the internet, but not to copy text directly; always write in your own words and refer to the source(s) you have used to come up with your answer.

Make sure to regularly save your answer file onto your computer while conducting the exam.

The file with your answers should be uploaded as a pdf file onto LMO before the deadline.

Turnitin will be used to detect plagiarism, copying and collusion.

Ethics

Regulation

Economics

Patents

Antibiotics and metagenomics

CRISPR

CRISPR/CAS IS AN ADAPTIVE IMMUNE SYSTEM IN BACTERIA

Exploiting the mechanisms

CRISPR array

Single-guide RNA-Cas9 complex hybridized to target sequence

Repair of DSB:HDR

Repair of DSB: NHEJ

Summary of CRISPR/Cas9

https://www.youtube.com/watch?v=MnYppmstxIs

Stem cellls

stem cells

Stem cell classes

ESC

Disadvantage of ESC

Disadvantages of iSPC

Hematopoietic Stem cells (HSCs)

GM food and animals

Biofuels

19-20 Past exams

Q1

Explain how different measures (within China or abroad) to prevent the transmission of SARS-CoV-2 and to treat COVID-19 could be labeled as “deontology” or “utilitarianism” based on the definitions given in the pdf file “The Basics of Philosophy – Ethics” provided on ICE (limit your answer to maximum 1000 words; 20 marks). Include references to each source of the examples you give in your answer (5 marks).

Deontology:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410812/

Utilitarianism:

Bowen, R., 2021. Ethical and organizational considerations for mandatory COVID-19 vaccination of health care workers: A clinical laboratorian’s perspective.

Q3

Explain how the interests of biotechnology companies clash with those of other stakeholders regarding the development and sales of new products (limit your answer to maximum 1000 words; 25 marks

answer

分析interests of biotechnology

一些细节和小点可以在ppt中获得

有哪些stakeholders

Q4

Explain what requirements need to be fulfilled to make DNA eligible for patenting and why this is beneficial for healthcare. Also provide three examples of existing patents that contain claims on DNA. Include references to your sources (limit your answer to maximum 800 words; 15 marks).

https://medlineplus.gov/genetics/understanding/testing/genepatents/

Describe what type of crop you would design by building in at least two exogenous genes and explain why. Include reference to peer-reviewed articles in your answer (limit your answer to maximum 600 words; 10 marks).